Endocrine Abstracts

Introduction and objectives: Hyperglycemia (HG) is a common problem in hospitalized patients that increases infections, mortality, costs and the hospital stay. The objective of this study is to know the association of the HG with cardiovascular risk factors (CVRF), stress factors, hospital stay and mortality.Methods: We designed a cross-sectional observational study. We included patients admitted in the hospital every three days in two months. We exclude...

Introduction and objectives: Hyperglycemia (HG) is a common problem in hospitalized patients that increases infections, mortality, costs and the hospital stay. The objective of this study is to know the association of the HG with cardiovascular risk factors (CVRF), stress factors, hospital stay and mortality.Methods: We designed a cross-sectional observational study. We included patients admitted in the hospital every three days in two months. We exclude...

Introduction and objectives: Hyperglycemia is a common problem in hospitalized patients that increases infections, mortality, costs and the hospital stay. The objective of this study is to know the management and control of hyperglycemia in our hospital.Methods: We designed a cross-sectional observational study. We included patients admitted in the hospital every three days in two months. We excluded patients younger than 15 years, stays less than three ...

Thyroid hormone plays an important role on carbohydrate and lipid metabolism. In hypothyroidism is observed reduction of glucose transporter-4 expression and insulin sensitivity and in hyperthyroid states the key enzymes of gluconeogenesis and glycogenolysis are induced, and both conditions lead to glucose intolerance. It has been reported an increased prevalence of thyroid dysfunction in obese and diabetic patients. Recently we have demonstrated a hypothyroid state in alloxan...

Hashimoto’s thyroiditis (HT) is the most common chronic autoimmune thyroid disease, which is characterized by alteration of the thyroid function. HT is a multifactorial disorder and several candidate genetic loci have been identified as contributing to HT. The transcription factor Nrf2, encoded by the NFE2L2 gene, is an important regulator of the cellular protection against oxidative stress. The relevance of selenoproteins in follicular thyroid cell physiology and in mole...

Introduction: The diagnosis of Cushing’s syndrome is often challenging considering that none of the used laboratory tests has an ideal diagnostic accuracy. The complexity of the diagnosis increases in cyclic disorder, which is characterized by repeated episodes of cortisol excess followed by periods of normal cortisol secretion.Case report: A 32-year-old woman with history of arterial hypertension and obesity presented with weight gain, hirsutism, a...

Introduction: Spontaneous fertility in Turner syndrome (TS) is rare, due to low or absent ovarian reserve. A greater number of ovarian follicules is present in the cases of gonadal mosaicism, although the accelerated pace of apoptosis remains. Thus, the early referral to reproductive counseling is advisable, ideally soon after diagnosis. The criopreservation of oocytes is one of the options for fertility preservation. The authors present a series of 7 patients with TS admitted...

Background: Transphenoidal surgery is still the best initial therapy for Cushing’s disease (CD), with a high probability of cure and few risks or complications. However, pharmacotherapy has a role as primary or adjunctive therapy: when surgery is delayed, in case of postoperative persistence or recurrence of hypercortisolism, or while waiting for radiotherapy effectiveness. Ketoconazole, a steroidogenesis inhibitor, is nowadays the main drug used to CD control by reducing...

Introduction: Endocrine Illnesses have high prevalence on a global level due to multiple etiologies that can lead alterations to this system.Objective: Determine the epidemiological profile of hyperthyroid and hypothyroid patients that receive endocrinological services from a medical institution in Medellin (Colombia) between 2013 and 2015.Methodology: A descriptive, retrospective study was conducted and included the clinical recor...

Introduction: The Bethesda System for Reporting Thyroid Cytopathology is the standard for interpreting fine-needle aspiration (FNA) and created a new diagnostic category (III): ‘atypia of undetermined significance/follicular lesion of undetermined significance’ (AUS/FLUS). The risk of malignancy for this category has been ascribed of 5–15% but the real malignancy rate remains unclear and plays a key role to define appropriate management.Ob...